Jared Padaleks in an interview with Entertainment Weekly unexpectedly said that, in his opinion, "either both must die, or Sam must die."
Jensen the vision of the final is quite a bit more optimistic - in an EW interview he admitted that the ending of the "supernatural" somehow had somehow dreamed, and it looked like this:
"I can imagine it at least now. Only one scene. Imagine: American depth, around to the horizon itself - only wheat fields and some intersection. I approach the imparal, I stop in the middle of the intersection, around the whole mile - no one. I go out of the car, peering into the distance from the "Lawrence of Arabian", when Omar Sharif drove on a camel - I see, first away, and then getting closer and closer, some kind of guy on a motorcycle. We do not show his faces, he is in the helmet. But he comes up to me, I nod, I wonder, very slowly, around the impala - and I stretch him the keys. And he removes his helmet - we still do not see who it is, - and stretches it to me together with the keys from the bike. He sits in the car, and I am watching the impala leaves. And then turning, I put it on a helmet, I'll buy a bike, you throw one last glance at the impalae in the distance - and I'm leaving. I even have a soundtrack in my head. Not a single word pronounced. As in some movie Robert Zeekis.
"It seems to me as if I know Jensen, I know Dina, I know Misha, I know Casa, I know myself, I know Sam, and when the series will end, it will be felt as if you lose a friend. When everything is over, it will be very difficult. I will lose several friends at once, "concluded Padaleks (and at this moment the editors were silent, yes).