Nkhani yachikondi MeredIS imvi ndi Derek Shepard adakondedwa kwambiri ndi omvera. Onse anali pafupi moyo ndi imfa kangapo. Wokondedwa opaka ndi kutenga mwana. Pambuyo pake, anali ndi mwana wawo, ndipo Meredith a Dereche adayamba kuganizira za wolowala dzanja. Aliyense anaphwanya imfa yomvetsa chisoni ya Shepard. Komabe, mafani ambiri amakhulupirira kuti neurosurgeon adapulumuka ndipo posakhalitsa zikuwonekera. Teaser gawo latsopano la nyengo yakhumi ndi chisanu ndi chiwiri
Nkhanizi zidawonetsa nkhani yopambana Dr. Shepard, yomwe imalumikizidwa ndi ngwazi yayikulu. Mu gawo la akatswiri, iye anali wodziwika bwino kwambiri, koma sanali mwayi ndi moyo wake. Pambuyo polekerera ndi mkazi wapitawu, amakhala ku Seattle, komwe adakumana ndi Medrintith Emm. Pambuyo pakubwera mosayembekezereka kwa wokwatirana naye, Derek akuyesera kukhazikitsa ubale ndi iye, koma amamvetsetsa zomwe zili mchikondi ndi Meredith. Zochitika zinayamba kukula mwachangu, motero imfa ya munthuyo idakhumudwitsa mafani ambiri.
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