Inkuru y'urukundo Meredith imvi na Derek Shepard yakundwaga cyane nabari aho. Bombi bari hafi yubuzima nurupfu inshuro nyinshi. Bakundwa barashushanyije kandi barera umwana. Nyuma yibyo, babyaranye, kandi Meredit hamwe na dereche batangira gutekereza ku muraro wa gatatu. Abantu bose bamennye urupfu rubabaje rwa Shepard. Icyakora, abafana benshi bizeraga ko Neurosurgeon yarokotse kandi bidatinze agaragara murukurikirane. Teaser yiki gice gishya cyigihembwe cya cumi na karindwi "anatomy yishyaka" yerekana ko Patrick DamSy izagaruka kumurimo wa alfictoator mugihe gishya.
Urukurikirane rwerekanye inkuru ya Dr. Shepard, ifitanye isano nintwari nyamukuru. Mu ruzitiro rw'umwuga, yari umwe mubyiza, ariko ntabwo yari afite amahirwe mubuzima bwe bwite. Nyuma yo gutandukana n'umugore wabanjirije, yabaga i Seattle, aho yahuriye na Meredith. Nyuma yo kuza mu buryo butunguranye n'uwahoze ari uwo bashakanye, Derek aragerageza gushiraho umubano na we, ahubwo yumve ibiri mu rukundo hamwe na Meredith. Ibintu byatangiye gukura vuba, nuko urupfu rwimico yatengushye abafana benshi.
"Anatooy y'ishyaka" iratangajwe ku wa kane ku muyoboro wa ABC. Vuba cyane, abumva bazashobora kubona imico ukunda kuri ecran.