Ibali lothando i-meredith grey grey noDerek Shepard bathandwa kakhulu ngabaphulaphuli. Zombini zazikwimeko yobomi nokufa izihlandlo ezininzi. Intanda yampeyintiwe kwaye yamkela umntwana. Emva koko, babenomntwana wabo, kwaye uMerides noDereche baqalisa ukucinga ngendlalifa yesithathu. Wonke umntu waphula into ekrwada kwe-shepard. Nangona kunjalo, abalandeli abaninzi babekholelwa ukuba i-neurosurgeon yasinda kwaye kungekudala ivele kwingcelele. UTeserr we-ofisi entsha yeshumi elinesixhenxe leminyaka "ye-anatomy ye-anatom" intembelo yokuba uPatrick Damy uza kubuyela kwindima ephezulu.
Olu ngcelele lubonise i-biline yebali eliyimpumelelo le-GR. Shepard, exhunyiwe ne-heroine enkulu. Kwinqanaba lobuchule, wayengomnye weyona nto ilungileyo, kodwa wayengenathamsanqa ebomini bakhe. Emva kokuhlukana nomfazi wangaphambili, wayehlala eSeattle, apho wadibana khona noMeredith. Emva kokufika okungalindelekanga kweqabane langaphambili, uDerek uzama ukumisela ubudlelwane naye, kodwa uyakuqonda oko kuthandana noMeredith. Iziganeko zaqala ukukhula ngokukhawuleza, ngoko ke ukufa komlinganiswa kuphoxekile abaninzi.
"I-anatomy ye-velotoon" isasazwa ngoLwesine kwi-ABC Channel. Kungekudala, abaphulaphuli baya kuba nakho ukubona umlinganiswa owuthandayo kwisikrini kwakhona.