NgoLwesihlanu olwedlule, uDan Eikroyd, owadlala enye yezindima eziphambili ku- "Ghostbusters" yasekuqaleni, waba yisimenywa seRadoshow Greg Hill. Ekuhambeni kwengxoxo, umlingisi ukuqinisekisile ukuthi uMthethosivivinywa Murray uzodlala uDkt Peter Venkman ku-Sequel ezayo ezayo ngo-1984. Ngaphezu kwalokho, ngokusho kwe-eykroyd, kwifilimu entsha kwiZondiso zayo ezinde futhi kuzobuyisela i-Sigarney Weaver, u-Ernie Hudson no-Annie Potts.
Ngenkathi uMqondisi kanye nombhali wezomthetho wesimo sezipoki (1984) futhi "abazingeli bezipoki 2" (1989) baba u-Ivan Rytman, indodana yakhe, uJason Raitman, yaqala ukudala iSikvel. Ngalesi sikhathi, u-Eikroyd uthe:
UJason wabhala isimo esijabulisayo nesisuka enhliziyweni sathatha i-DNA yamafilimu amabili okuqala awudlulisele engxenyeni yesithathu kuyo, okungukuthi, esizukulwaneni esisha sababukeli. Ifa lika- "Ghost Hunters" lizodluliselwa esizukulwaneni esisha sezinkanyezi, abadlali kanye nezinhlamvu.
"Abazingeli bezipoki" uJason Rytman bazokhishwa ngohlobo oluthile ngonyaka olandelayo. Kanye nama-veterans of the franchise kwifilimu entsha, abaculi bazodlala kanjena Paul Rudd, Carrie Kun, Mackenna Race, kanye nenkanyezi yochungechunge "lwebhizinisi oluxakile" uFinn Wolfeard.
