UCharles Bulfrass umemezela ukuthi umbhali wesayensi ye-Opera Efera Exogenesis, okubandakanya i-Symphony enezingxenye ezintathu. Ngokusho kwakhe, wethule lesi simo se-opera yakhe emaqenjini amathathu omculo, phakathi kwabo ayenguMnyuziyamu. Kepha akekho owaba nesithakazelo emcabangweni wakhe. Ngokusho kwendaba ye-rock opera, izwe liseduze kokubhujiswa nobuntu buphoqeleka ukuba babheke izindlela zokusindiswa. Kwi-albhamu okuphikiswa ngu-2009, iqembu leMuse linokwakhiwa kwe-exogeneis: I-Symphony Part 1 (i-Exokeni: I-Symphony Partture 2 (i-Symphony Partture 3 (Ukuhlengwa Ingxenye 3 (Ukuhlengwa Ingxenye 3 (Ukuhlengwa), okuthi, ngokwe-Charles Bulfrass, futhi bangobunye izindaba kuye. Ummeleli weqembu uyaphika ukulunga kwamacala, athi: "Izitatimende zakhe zigcwele ububi. Basho ukuthi izingoma zisuselwa esimweni sokuthi le qembu alikaze libone lelo qembu. The I-albhamu yakhishwa eminyakeni emithathu edlule, kodwa ngezicelo zakhe le ndoda yanquma ukumemezela kuphela manje - kusho abaningi. "